Friday, October 23, 2009

Alternative Cancer Treatments

I found the point of sameness of plant based food and potential of cancer cure.



the point of sameness of plant based food is the Lack of calories.


When cancer patient is starving, the blood sugar level and the concentration of amino acid is getting lower.

normal cell need only few nutrition. In few nutrition, perhaps normal cell doesn't divide. only few of essential part will divide cautiously.

cancer cell always tries to divide even if cancer patient is starving.

this difference is very important to cancer cure. Even if same amount of nutrition is supplied for cancer cell and normal cell, cancer will be starving and will die with starving in few nutrition supply but normal cell leave some nutrition in few nutrition supply because of supplied nutrition is much more than its need.

I guess that the side effect of starving can be controled while starve as a cancer treatment.

Since I found this imfortant fact, I sent e-mail to many cancer institute many countries but they never responded for me.



korean entertainer(TV star) Lee Eui Jung got a brain tumor, size of tumor is 7cm(2~3inch).

her doctor said that her life left 3months to 18months in 10,July,2006.

2 months after without any chemo therapy or surgery, her tumor almost disappeared size of tumor is smaller than 1cm. and doctor found some inflammation around tumor.

1 year after doctor said to her "I guess that you cured brain tumor completely!"

Lee Eui Jung said "I became fat since tissue examination. while take a tissue examination, my brain get some damage so I can't feel contentment of my stomach.and I always feel so hunger. when my waist size became 32inch I decided to go on a diet. My father allowed me only half bowl of boiled rice in a day. Once, some day because of my hunger I take dog's food from dog for eating."


the strory of TV star Lee Eui Jung is real. I attached a link about brain tumor and Lee Eui Jung and believable source


this is internet english news. but It's doesn't give full detail of her fight story about brain cancer. If you can read korean you can find more detail.





http://kpopfan.com/lee-eui-jung-makes-her-comeback-as-a-singer-137th/



http://www.yesasia.com/us/lee-eui-jung-reengaging/1021216665-0-0-0-en/info.html



http://www.allkpop.com/index.php/full_story/lee_eui_jung_makes_her_comeback_as_a_singer/







half bowl of boiled rice is only 150kcal. I guess that it maybe important evidence.

When cancer die with starving, the dead tissue of cancer tumor is not the cell of the cancer's owner. owner of cancer tumor rejects(Medicine. The failure of a recipient's body to accept a transplanted tissue or organ as the result of immunological incompatability; immunological resistance to foreign tissue.) dead tissue of cancer tumor

any dead tissue of normal cells also induces rejection. every dead tissue destroyed by white blood cell. when white blood cell destroys dead tissue, surrounding cells of dead tissue also destroyed by white blood cells. so survivors(survived cancer cells) in few nutrition also destroyed by free radical of white blood cells. free radical is strong weapon of white blood cell. white blood cells make free radical from oxygen. free radical destroys every thing no matter what this is reason that why surrounding cells of dead tissue also destroyed.

inflammation is symptom of free radical.



Many people believe that vegetarian diet is good for cancer. And many scientist tried to find out certain factor which is important thing as cancer treatment from vegetables and fruits. But, remarkable factor is not revealed in the world. So this writing is for the discovery of the factor. And perhaps side effect of surfeit of vegetable is the factor. For determine whether low blood sugar which is side effect of surfeit of vegetable is the main factor or have no relation to death of cancer, amount of sugar essential and total of sugar supply are partially calculated.

A human cell has about 2.8billion(1) base pairs(or about 5.6 billion base) and 2.8billion base pairs have 11.2 billion deoxyriboses as a DNA back bone(2). Deoxyribose and glucose are sugar. So glucose maybe used as a raw material of DNA back bone. And for 1.12e+10 deoxyriboses, 3.3477e-12 g glucose may be essential as a raw material of deoxyriboses.

The number of cancer cells is about 2000/mm^2(3) and the density of microvessel is about 200(count)/mm^2(3) and the average diameter of microvessels is about 10μm(). One microvessel of 200 microvessels in 1cm length of tumor is surrounded by 4472 cancer cells.

2000/mm^2 times sqrt{2000/mm^2} times 10mm div 200/mm^2 approx 4472.136 The concept of a cancer cell is a point. And the concept of a microvessel is a line.

Cancer cells which surround one microvessel must needs 1.4971e-8 g glucose per 1cm as the raw material of the deoxyriboses.

The blood flow velocity is about 0.49 mm/sec in capillaries(4). If the average blood sugar level is 100mg/dl, total amount of glucose which passes through a microvessel of10μm diameter is 3.323376e-6g/Day.

1.4971e-8 g is about 0.45% of 3.323376e-6g. But it's not calculated that how percent of 3.323376e-6g glucose is absorbed by 4472 cancer cells. And it's sure that 4472 cancer cells consume more glucose than 1.4971e-8 g.

For calculating the percent of the absorption, osmotic pressure and diffusion velocity must be considered. And it must not ignored that the convection must be limited among the cancer cells.

Most cancer cells starve(die) and 4% of survived cells induce KRAS Pathway Mutations in 9mg/dl glucose(5). This means that low blood sugar induce the necrosis of cancer cells. Besides, the density of microvessels in tumor have relation to cancer returns(6).

Under 70mg/dl glucose in micorvessels may reach under 9mg/dl glucose among cancer cells. One microvessel manages about 40μm from itself. 40μm is 8 times of radius of microvessel of 10μm diameter. Cancer cell which closes to microvessel will absorbs more sugar than enough so another cell may absorbs less sugar than essential amount. Besides, the glucose concentration in a micorvessel of the cancer tumor will be getting lower as blood flows(figure1). Figure1 explains that why huge tumor have disadvantages in low blood sugar level.

The calculation is not completed. But if someone completes this calculation, every things will be sure. Or if someone who has cancer maintains low blood sugar level(under 70mg/dl), we can know the relation between blood sugar level and cancer growth.

At last, the change of dietary has relation to avoid cancer death(7) no matter that the relation are strong or not. The important thing is that perhaps the induced low blood sugar by vegetable based diets are the main reason to avoid cancer death. The concentration of amino acid also needs to consider.

The purpose of this writing is to informing that to maintaining low glucose may be better treatment than chemotherapy. All of cancer patients have to know that perhaps to maintaining low blood glucose(always under 70mg/dl) is enough good as a new cancer treatment.

Figure1. Conception of glucose loss when blood flows : As blood flows, concentration of glucose is getting lower as cancer cell absorb much glucose.

e-mail : evilstriver@hanmail.net

reference

1. http://en.wikipedia.org/wiki/Chromosome#Human_chromosomes

2. Levene P, (01 December 1919). "The structure of yeast nucleic acid". J Biol Chem 40 (2): 415?24. http://www.jbc.org/cgi/reprint/40/2/415.

3. Tsuyotoshi Tsuji, Yoshihiro Sasaki, Masanori Tanaka, et al: Microvessel Morphology and Vascular Endothelial Growth Factor Expression in Human Colonic Carcinoma With or Without Metastasis. Lab Invest 2002, 82:555?562

4. M.Stucker, V. Baier, T. Reuther, et al. Capillary Blood Cell Velocity in human skin capillaries located perpendiculary to the skin surface: Measured by a New Laser doppler anemometer. Microvascular research 52, 188-192(1996)

5. Jihye Yun, Carlo Rago, Ian Cheong, et al. Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells. Science DOI: 10.1126/science.1174229

6. Noel Weidner. Intratumor Microvessel Density as a Prognostic Factor in Cancer. American Journal ofPathology, Vol. 147, No. 1, July 1995

7. WC Willett: Diet, nutrition, and avoidable cancer. Environmental Health Perspectives 103:165-170, 1995 (suppl 8)


How can I maintain low blood sugar level?
In 24 April 2009, I realize that many kinds of vegetable based diets have a point of sameness. the point of sameness is that vegetable based diets have only few calories.





Besides the corpulence relates to growth of cancer tumor and cancer return.





In culture tool, the concentration of glucose(blood sugar) is 500mg/dl(0.5% glucose). the speed of cancer cell division is maximum when the concentration of glucose reaches 0.5%( 500mg/dl). the maximum speed of cancer cell division is once per 18 hours.





The average blood sugar level of normal is 0.1~0.13%(100~130mg/dl). the blood sugar level reaches above 0.16~0.17% when 30 minutes after meals.




In 0.009%(9mg/dl or 0.5mM) glucose, most cancer cell dies of hunger.





And in under 0.05% glucose, human body start to get damage.





So, to maintaing 0.05~0.07%(50~70mg/dl) blood sugar level is not harmful to human but it is harmful to cancer tumor. All cancer cells of tumor gain Glucose(glucose is essential for to make energy) from blood of the near microvessels.




To maintaing 0.05~0.07%(50~70mg/dl) blood sugar level may induces 0.009%(9mg/dl or 0.5mM) glucose partially in among cancer cells of tumor.





And when some cancer cell dies, those material of dead cells(in other word, dead cell's body) are destroyed with surrounding cells(Which are survived) by white blood cell(or macrophage).




the material of dead cells induce the rejection(Medicine. The failure of a recipient's body to accept a transplanted tissue or organ as the result of immunological incompatability; immunological resistance to foreign tissue). And The circumference of the material of dead cells will be destroyed by the rejection.




~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~


Above is a theory and following is method of maintaing 0.05~0.07%(50~70mg/dl) blood sugar level.


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~





For 7days,





Take three meals in a day without any fat(doesn't matter plant based fat or not) and protein




the amount of meals(which is vegetable based diets) must be under 30% of normal amount(under 200~300kcal)





when you get hunger, eat cabbages or radishs or etc(etc means vegetable which have few calories like cabbages).





drinking vegetable juice is not good idea. just eat raw cabbages of ect.





when you feel the weakness of your body take one banana.





Take some exercise 15 minutes after meals for to prevent blood sugar from getting high and for to maintaing your muscle. Maintain the exercise for 30 minutes





You may need a running machine. Immoderate exercise is not good for you. don't be excessive.








---------------------------------


For 3 days, after above 7days.





For to maintaing your health and muscle,




Take three meals(with some protein like beans based food) in a day without any fat(doesn't matter plant based fat or not).





the amount of meals must be normal





when you get hunger, eat cabbages or radishs or etc(etc means vegetable which have few calories like cabbages).





drinking vegetable juice is not good idea. just eat raw cabbages of ect.





Eat one boiled egg per Day.





For the First day of 3days,





Take some exercise 15 minutes after meals for to prevent blood sugar from getting high and for to maintaing your muscle. Maintain the exercise for 30 minutes





For the second day and third day of Three days,





Take more hard exercise than normal 15 minutes after meals for to prevent blood sugar from getting high and for to maintaing your muscle.





Maintain the exercise for 35~45 minutes.





----------------------------------------------








And repeat the 7days and 3days diet.





Why I have to eat 3days diet?




This is because short meal induce low weight. And for to maintaing low blood sugar level, lower weight need only lower intake of calories. In other word, 3days diet is because cancer patients need to prevent this vicious circle.




Exercise induce high concentration of oxygen in the cancer tumor.





And High concentration of oxygen forbids the creation of the microvessels(=capillaries) and destroys the microvessels(These are different Mechanisms) and maintains low blood sugar.





This is because exercise good for cancer.





I'll pray for your health sincerely. Your Willing will be always with your God. And the pain is the trial that you have to fight.





So I wish that your willing overcome the pain. To give up the hope is just to kill yourself.





Above treatment method was not proved, but even if it's not proved method, it has enough values for try.





This is just a first try, but it has high realistic possibility.






the point of sameness of plant based food is the Lack of calories.



I am sure that this treatment method must work.


The purpose of this writing is to informing that to maintaining low glucose may be better treatment than chemotherapy. All of cancer patients have to know that perhaps to maintaining low blood glucose(always under 70mg/dl) is enough good as a new cancer treatment.
http://en.wikipedia.org/wiki/Talk:Cancer#To_Maintaining_Low_Blood_Sugar_as_a_New_Cancer_Treatment
How can I maintain low blood sugar level?
http://eviltocancer.blogspot.com/2009/10/how-can-i-maintain-low-blood-sugar.html



pharmaceutical[drug] companies hide somthing too important



Cancer cell Can divide in two whitin 18~19hours in culture nutrition materials.



But in human body, cancer dividing velocity can not reach once per 18hours



This is because the concentration of sugar(glucose) is different between culture nutrition materials and human blood.



the glucose concentration of culture nutrition materials is 500mg/dl



and the glucose concentration of human blood is 70~170mg/dl(average is about 100mg/dl)



the concentration of sugar and the concentration of amino acids and the concentration of phospholipid are the important factor of cancer tumor growth velocity.



starving is much better treatment than chemo therapy.



chemo therapy destroy the peripheral blood much more than cancer tumor.



So chemo therapy can not cure cancer.



But side effect of chemo therapy(anorexia) can cure cancer.



straving is much better treatment than chemo therapy. But pharmaceutical[drug] companies hide the truth. It is because Starving is mortal factor for their drug selling business.



under 50mg/dl glucose is harmful. but 50~70mg/dl glucose isn't harmful



and the 50~70mg/dl glucose can delay the growth of cancer. perhaps the 50~70mg/dl glucose can cure cancer.



the 50~70mg/dl glucose can delay the formation of microvessels. lack of microvessels in cancer tumor make cancer cells hungry.

I ignored

Response to your Query : - Ref:DE00000451398 - To Maintaining Low Blood Sugar as a New Cancer Treatment 관련제목검색
2009년 10월 23일 금요일, 오후 18시 49분 49초 +0900
evilstriver@hanmail.net 추가

DE00000451398

Dear Sir or Madam,

Thank you for your email of 15 October to the Department of Health about the treatment of cancer.

I should explain that it is for healthcare professionals to decide on the most appropriate treatments for their patients, and it is for local NHS organisations to decide what treatments they will fund. The Department does not investigate new treatments.

I am sorry I could not be more helpful.

Yours faithfully,

Louise Marks
Customer Service Centre
Department of Health


The original of this email was scanned for viruses by the Government Secure Intranet virus scanning service supplied by Cable&Wireless in partnership with MessageLabs. (CCTM Certificate Number 2009/09/0052.) On leaving the GSi this email was certified virus free.
Communications via the GSi may be automatically logged, monitored and/or recorded for legal purposes.

Wednesday, October 7, 2009

Fucking idiot



Macdonald Ogaraku and sons law chambers. 관련제목검색
2009년 10월 07일 수요일, 오후 16시 02분 54초 +0900
ogareku_lawfirm@yahoo.fr
악마의히든카드 추가

Macdonald Ogaraku and sons law chambers.
No.42 rue de plateau avenue
abidjan cote d'ivoire.


Attention;

Respected,

Find via email and attachedment, the outcome of our verification exercise at the ministry of finance and interior on your behalf from the ministry of finance and interior.

We confirmed your beneficiary status to be correct and approved by the commissioner of oath from the ministry of justice as it was stated in the affidavits that declares you the new beneficiary of the fund, you are therefore requested to pay for the legal fee of ($2,950 US Dollar) for us to carry on with the documents procurement from the ministry of finance and interior.

Be restful assured of our total corporation upon your compliance.

You have to send the fee through the name of my secretary for urgent receive and earliest service.

Below are the information’s for the payment.

Receiver’s name: Agnes Kpegnan,
Address: Rue du commerce immeuble 4eme etage 6eme Porte Abidjan
Country: Cote d'ivoire .

Go ahead and make the payment immediately through western union for urgent receiver, and inform us on phone or by email for withdrawer so that we can effect the procurement of the vital requirements comprehensively.

As soon as we receive the legal fee for the documents on your behalf, we will make sure that the vital papers are obtained within two days.

Attached is an agency appointment form which you should sign and send back to us via attachment together with the payment slip information’s.

Yours in service,
Hon. Barrister Macdonald Ogaraku Esq.
Principal attorney.




Dearest In Christ ,

Greetings to you in the mighty name of our Lord Jesus Christ, i am very happy for your response to my mail, well i am not afriad of the death because i knows where i am heading to, my only problem is to see the desire of my late husband come to accomplishment now that i am alive, so dearly one in Christ i want you to assure me that you will never let the trust i have in you down, that you will use the fund accondingly to the will of the Almighty God.
I know you are surprise in receiving this letter, but as a servant of the living God, you should know that our ways is not his ways, my Bible tells me that God works in many ways and all things works out for good to them that believed in Christ Jesus, all i need from you is to assure me that you will never betray the trust i am trying to entrust in your hand for the work of God, you may asked me how i got across your email, the bilbe said that who is me is greater than who of the world, the Holy Spirit that leads me to you will never let us down only if you can beleive with faith.
Please, I want you to understand that this benevolence is in fulfilment of the desire and decision of my late husband which I am persuaded to actualize,this fund is desiginated for humanitarian and Charity services with special emphasis, which must be disbursed with every appropriation, accountability and prudence to the glory of God.

I will want you to send to me your full names and address to enable me swear an affidavit on oath on your behalf that will officially and legally approve you as the new beneficiary to this fund, so that even if i am no more, your claim to the fund will not be in doubt. I will be sending you the certificate of deposit of this fund immediately after the affidavit is ready.

I will want you to kindly be fast on your arrangement on how the fund will be transfered to you before the fall of the crises in Ivory Coast, since the political affair has affected their economy. Infact, the saints have been fasting and praying for peace for the country since the attacked of the rebels.

Ensure you reply this letter and the needed information immediately for the proccess of this transaction on your behalf.
Most Important: I will like this to be so confidential and sincerelity, also bear in mind that can not call you on phone, all our comminucation will be via-email because of my late husband relatives.
Thanks and may God bless us all.
Sister Rebecca Williams.

Note: I have attached the photo of my myself.I will be glad to have yours if possible

Sunday, October 4, 2009

How can I maintain low blood sugar level?

In 24 April 2009, I realize that many kinds of vegetable based diets have a point of sameness. the point of sameness is that vegetable based diets have only few calories.


Besides the corpulence relates to growth of cancer tumor and cancer return.


In culture tool, the concentration of glucose(blood sugar) is 500mg/dl(0.5% glucose). the speed of cancer cell division is maximum when the concentration of glucose reaches 0.5%( 500mg/dl). the maximum speed of cancer cell division is once per 18 hours.


The average blood sugar level of normal is 0.1~0.13%(100~130mg/dl). the blood sugar level reaches above 0.16~0.17% when 30 minutes after meals.


In 0.009%(9mg/dl or 0.5mM) glucose, most cancer cell dies of hunger.


And in under 0.05% glucose, human body start to get damage.


So, to maintaing 0.05~0.07%(50~70mg/dl) blood sugar level is not harmful to human but it is harmful to cancer tumor. All cancer cells of tumor gain Glucose(glucose is essential for to make energy) from blood of the near microvessels.


To maintaing 0.05~0.07%(50~70mg/dl) blood sugar level may induces 0.009%(9mg/dl or 0.5mM) glucose partially in among cancer cells of tumor.


And when some cancer cell dies, those material of dead cells(in other word, dead cell's body) are destroyed with surrounding cells(Which are survived) by white blood cell(or macrophage).


the material of dead cells induce the rejection(Medicine. The failure of a recipient's body to accept a transplanted tissue or organ as the result of immunological incompatability; immunological resistance to foreign tissue). And The circumference of the material of dead cells will be destroyed by the rejection.


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Above is a theory and following is method of maintaing 0.05~0.07%(50~70mg/dl) blood sugar level.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~


For 7days,


Take three meals in a day without any fat(doesn't matter plant based fat or not) and protein


the amount of meals(which is vegetable based diets) must be under 30% of normal amount(under 200~300kcal)


when you get hunger, eat cabbages or radishs or etc(etc means vegetable which have few calories like cabbages).


drinking vegetable juice is not good idea. just eat raw cabbages of ect.


when you feel the weakness of your body take one banana.


Take some exercise 15 minutes after meals for to prevent blood sugar from getting high and for to maintaing your muscle. Maintain the exercise for 30 minutes


You may need a running machine. Immoderate exercise is not good for you. don't be excessive.



---------------------------------

For 3 days, after above 7days.


For to maintaing your health and muscle,


Take three meals(with some protein like beans based food) in a day without any fat(doesn't matter plant based fat or not).


the amount of meals must be normal


when you get hunger, eat cabbages or radishs or etc(etc means vegetable which have few calories like cabbages).


drinking vegetable juice is not good idea. just eat raw cabbages of ect.


Eat one boiled egg per Day.


For the First day of 3days,


Take some exercise 15 minutes after meals for to prevent blood sugar from getting high and for to maintaing your muscle. Maintain the exercise for 30 minutes


For the second day and third day of Three days,


Take more hard exercise than normal 15 minutes after meals for to prevent blood sugar from getting high and for to maintaing your muscle.


Maintain the exercise for 35~45 minutes.


----------------------------------------------



And repeat the 7days and 3days diet.


Why I have to eat 3days diet?


This is because short meal induce low weight. And for to maintaing low blood sugar level, lower weight need only lower intake of calories. In other word, 3days diet is because cancer patients need to prevent this vicious circle.


Exercise induce high concentration of oxygen in the cancer tumor.


And High concentration of oxygen forbids the creation of the microvessels(=capillaries) and destroys the microvessels(These are different Mechanisms) and maintains low blood sugar.


This is because exercise good for cancer.


I'll pray for your health sincerely. Your Willing will be always with your God. And the pain is the trial that you have to fight.


So I wish that your willing overcome the pain. To give up the hope is just to kill yourself.


Above treatment method was not proved, but even if it's not proved method, it has enough values for try.


This is just a first try, but it has high realistic possibility.

Friday, September 25, 2009

Original of cancer formation



-------------------------------------------------------------------------------------------------------

{Contradiction

These two sentences seem to contradict eachother. Can someone who knows how this is supposed to read make it more clear?

"Substances that cause DNA mutations are known as mutagens, and mutagens that cause cancers are known as carcinogens."

"Many mutagens are also carcinogens, but some carcinogens are not mutagens."}


http://en.wikipedia.org/wiki/Talk:Cancer#Contradiction

--------------------------------------------------------------------------------------------------


Talk for above


To Avoid the Contradiction, you must Deny that cancer is mutation cell. but most scientists believe that cancer is mutation cell. But straight evidence is not revealed. anyway some cancer cell have mutated position.


DNA mutations some times mean just changed DNA base pair. But some times mutations mean to mutate with evolution and certain function. The former mutations are simple but the latter mutations have huge mystery that is hard to explain.

"Substances that cause DNA mutations are known as mutagens, and mutagens that cause cancers are known as carcinogens."

In above sentence, I also have a doubt in statistics. There are too many cancer patients to say cancer cell is mutation cell.

Some cancer is virus based cancer. But other cancer is spontaneous cancer. And spontaneous cancer have short telomere(1) at last in this article and HeLa(HPV-18 positive cell line, virus based cancer) have long telomere(another virus based cancer have short telomere, it means that virus based cancer have no relation to the lenght of telomere).

"These two sentences seem to contradict eachother."

In above sentence, I agree your opinion. Some cancer cell have detectable mutation part. It means that some other cancer have not detectable mutation part. This is just guess but perhaps spontaneous cancer is not mutation cell.

Following is not proved and It is just a doubtful guess. But it's not swindle from a dishonest motive

Spontaneous cancers without any virus positive are maybe Programed Life Death(PLD) for generation shift. Human gene programed senescence and death as the process of generation shift. But some old man(The meaning of short telomere is old) doesn't concede his right to the next generations. So gene let him surrender his right to the next generations and die with induced tumor. In the wild, old animal get hunger so easily because of its weak power. But human's hunger doesn't depend on his or her physical power. Above tells about the ingestion of enough calories and the cancer formation

Short telomere have strong relation to spontaneous cancers at last in this article(1, full text of this article is free. Before read this article, you have to know that HeLa is HPV-18 positive cell line in other word virus based cancer) Above tells about the short telomere and the cancer formation

So perhaps the short telomere and the ingestion of enough calories are the key to cancer rise as a PLD. Cancer formation may be induced when somatic cells which have short telomere are exposed to urge to divide themselves. And virus negative cancer cell may divides itself without any lost of telomere length.

P.s

"Most cancer cells starve(die) and 4% of survived cells induce KRAS Pathway Mutations in 9mg/dl glucose(In To Maintaining Low Blood Sugar as a New Cancer Treatment, this writing exists just above in this pase)"

In above sentence, "KRAS Pathway Mutations" means the evolution for more intake of sugar and survival

some threat of life causes corresponding mutations(evolution) rarely. In other word, "KRAS Pathway Mutations" mean 0.5mM(9mg/dl) glucose is pretty strong threat for cancer cells.


REFERENCES


1.de Lange T, L Shiue, R M myers, et al: Structure and variability of human chromosome ends. Molecular and Cellular Biology 10:518-527, 1990

Evilstriver (talk) 04:19, 25 September 2009 (UTC)

Wednesday, September 23, 2009

Hypoglycemia and Cancer tumor;To Maintaining Low Blood Sugar as a New Cancer Treatment


To Maintaining Low Blood Sugar as a New Cancer Treatment

Many people believe that vegetarian diet is good for cancer. And many scientist tried to find out certain factor which is important thing as cancer treatment from vegetables and fruits. But, remarkable factor is not revealed in the world. So this writing is for the discovery of the factor. And perhaps side effect of surfeit of vegetable is the factor. For determine whether low blood sugar which is side effect of surfeit of vegetable is the main factor or have no relation to death of cancer, amount of sugar essential and total of sugar supply are partially calculated.

A human cell has about 2.8billion(1) base pairs(or about 5.6 billion base) and 2.8billion base pairs have 11.2 billion deoxyriboses as a DNA back bone(2). Deoxyribose and glucose are sugar. So glucose maybe used as a raw material of DNA back bone. And for 1.12e+10 deoxyriboses, 3.3477e-12 g glucose may be essential as a raw material of deoxyriboses.

The number of cancer cells is about 2000/mm^2(3) and the density of microvessel is about 200(count)/mm^2(3) and the average diameter of microvessels is about 10μm(). One microvessel of 200 microvessels in 1cm length of tumor is surrounded by 4472 cancer cells.

2000/mm^2 times sqrt{2000/mm^2} times 10mm div 200/mm^2 approx 4472.136 The concept of a cancer cell is a point. And the concept of a microvessel is a line.

Cancer cells which surround one microvessel must needs 1.4971e-8 g glucose per 1cm as the raw material of the deoxyriboses.

The blood flow velocity is about 0.49 mm/sec in capillaries(4). If the average blood sugar level is 100mg/dl, total amount of glucose which passes through a microvessel of10μm diameter is 3.323376e-6g/Day.

1.4971e-8 g is about 0.45% of 3.323376e-6g. But it's not calculated that how percent of 3.323376e-6g glucose is absorbed by 4472 cancer cells. And it's sure that 4472 cancer cells consume more glucose than 1.4971e-8 g.

For calculating the percent of the absorption, osmotic pressure and diffusion velocity must be considered. And it must not ignored that the convection must be limited among the cancer cells.

Most cancer cells starve(die) and 4% of survived cells induce KRAS Pathway Mutations in 9mg/dl glucose(5). This means that low blood sugar induce the necrosis of cancer cells. Besides, the density of microvessels in tumor have relation to cancer returns(6).


Under 70mg/dl glucose in micorvessels may reach under 9mg/dl glucose among cancer cells. One microvessel manages about 40μm from itself. 40μm is 8 times of radius of microvessel of 10μm diameter. Cancer cell which closes to microvessel will absorbs more sugar than enough so another cell may absorbs less sugar than essential amount. Besides, the glucose concentration in a micorvessel of the cancer tumor will be getting lower as blood flows(figure1). Figure1 explains that why huge tumor have disadvantages in low blood sugar level.

The calculation is not completed. But if someone completes this calculation, every things will be sure. Or if someone who has cancer maintains low blood sugar level(under 70mg/dl), we can know the relation between blood sugar level and cancer growth.

At last, the change of dietary has relation to avoid cancer death(7) no matter that the relation are strong or not. The important thing is that perhaps the induced low blood sugar by vegetable based diets are the main reason to avoid cancer death. The concentration of amino acid also needs to consider.

The purpose of this writing is to informing that to maintaining low glucose may be better treatment than chemotherapy. All of cancer patients have to know that perhaps to maintaining low blood glucose(always under 70mg/dl) is enough good as a new cancer treatment.

Figure1. Conception of glucose loss when blood flows : As blood flows, concentration of glucose is getting lower as cancer cell absorb much glucose.


e-mail : evilstriver@hanmail.net


reference


1. http://en.wikipedia.org/wiki/Chromosome#Human_chromosomes


2. Levene P, (01 December 1919). "The structure of yeast nucleic acid". J Biol Chem 40 (2): 415–24. http://www.jbc.org/cgi/reprint/40/2/415.

3. Tsuyotoshi Tsuji, Yoshihiro Sasaki, Masanori Tanaka, et al: Microvessel Morphology and Vascular Endothelial Growth Factor Expression in Human Colonic Carcinoma With or Without Metastasis. Lab Invest 2002, 82:555–562

4. M.Stucker, V. Baier, T. Reuther, et al. Capillary Blood Cell Velocity in human skin capillaries located perpendiculary to the skin surface: Measured by a New Laser doppler anemometer. Microvascular research 52, 188-192(1996)



5. Jihye Yun, Carlo Rago, Ian Cheong, et al. Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells. Science DOI: 10.1126/science.1174229

6. Noel Weidner. Intratumor Microvessel Density as a Prognostic Factor in Cancer. American Journal ofPathology, Vol. 147, No. 1, July 1995


7. WC Willett: Diet, nutrition, and avoidable cancer. Environmental Health Perspectives 103:165-170, 1995 (suppl 8)

Tuesday, September 8, 2009

oh..

I'm waiting for this...z

Monday, August 31, 2009

암세포 분열시 재료로사용되는 설탕의 양 calculates

염색체수 46개
염색체 1개의 염기수 30억쌍

30억쌍의 deoxyribose의 갯수 60억개

세포하나에 들어있는 디옥시 라이보오스의 수 46*6*10^9 = 2.76e+11 개


글루코오스의 분자량 180

디엔에이전사에 필요한 글루코오스의 수는 46*6*10^9 = 2.76e+11 개이며 무게로는

8.25e-11g 이다.

(180*46*6*10^9) / (6.022*10^23) = 약 8.25g * 10^-11

12시 47분 작성

Wednesday, August 12, 2009

some programe for 'USB device is not recognized' problem only xp

It works only XP Just downlode and run this program and retry for USB memory driver.


downlod here just copy and paste the URL

http://mfiles.naver.net/be648a54441574c895/20090812_105_blogfile/extra_rozer_1250070149337_4ZW07U_exe/iDevice.exe


P.s ; If you have an interest at new cancer treatment, take this imformations...

I have the method to destroy cancer but protect right cell. Poor calories made to starving, especially cancer tumor is easy to starving. Because Cancer is the wasting cells that cunsume highest energy for its groth. cunsume highest energy means easy to starving. Thus, if a cancer patient ingest only poor calories for a day, his or her cancer tumor must goes to starving

Amount of blood flow in one capillary is below 1.7 mL * 10 ^ -5 = 0.000017 mL per day. Only 0.000017mL/day means the cancer's own life depend on blood sugar level and times of that each levels

Cancer patient may overcome the cancer because of malnutrition


Cancer patient may overcome the cancer with malnutrition.(Caution, It's only speculation without animal test because of my poorness)or The disadvantage of cancer in poor environment


I'm sorry about my awkward writing. I have just little english skill(I'm a foreigner). And I have no purpose that indispose you. That's the reason I'm sorry.


Cancer is disease and causes some malnutrition. But malnutrition causes what? It can cause dying? Some cancer that link up with hepatic portal vein or organs of digestion maybe can.(I guess) But many cancer patients are not serious malnutrition as you know. At last, in my knowledge, only few cancers cause serious malnutrition. So I guess the position of cancer is the important reason of serious malnutrition.(It has no evidence but theory; my subjective theory)

In my subjective theory, cancer generally absorbs sugar from blood but in special position(For example the hepatic portal vein), it can absorbs the sugar from nourishment before spread on the blood. Absorbing the sugar from nourishment cause serious malnutrition like some mass of helminths.

My genial sense aimed to take interest in malnutrition. Because my genial sense caught the fact from the people who overcame the cancer. In this fact, the most of them had an experience of some malnutrition that was caused by eating and drinking problems while the cancer exists.

In the common nature, cancer has no advantage and just absorbs the sugar from blood like a normal cell. But, generally, cancer absorbs much more sugar than normal cell does. Unfortunately, but actuality it means 'fortunately' for human beings, it can't be elucidated by cancer's absorbing ability. cancer has absorbing ability just like a normal cell has. Because normal cell and cancer are perfectly same cells like twins except few point. It's the problem of tendency but not the problem of competence. Cancer is not stronger than normal cells. Normal cell has a tendency to absorb sugar properly when it is necessary to maintain itself. But cancer absorb sugar as much as possible as it consumes much sugar for the segmentation and the growth. Normal cell can control itself in poor environment but cancer can not(cancer includes 'can', why can not? why it isn't can 'cer'? "......" it just a joke, sorry.). It's the important difference between cancer and normal cell. This difference may be the reason of miracle that the cancer get destroyed.

Now, I'll try to explain the disadvantage of cancer in poor environment with this difference. If you can't believe me, I'll tell you "As you will". Whatever your choice it is your own right. I'll do not force you to believe me. But I'll trust my own argument.

Before the explain, I'll put some facts and some speculations on this paper for easy explain.

1. Cancer gain nutriment and oxygen from capillary

Cancer gain nutriment and oxygen from capillary(Exactly, the blood in the capillary). This is true but I don't know who discover this fact. Anyway, the growth of cancer is too fast to make capillary for normal capillary cells. So the oxygen is stingier than that cancer want to cost. and the lack of oxygen promote the growth of capillary. {Biochemistry 6th edition, Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, 438page, figure 16.21 Alteration of gene expression in tumors owing to hypoxia(hypoxia means the lack of oxygen)} As you know, hypoxia is related to anaerobic process. And anaerobic process cost much more glucose than aerobic process for same ATP.

2. One of reason that cancer costs much sugar may be anaerobic process.

3. cancer costs much sugar

I learned that cancer costs much sugar in university inorganic chemistry class. Professor tell us that cancer likes sugar and this character used for detecting cancer(Exactly, PET; positron emission tomography. that uses sugar with chase branch. I'm not sure the chase is a radioactive isotope or not. Exactly, I forgot that.)

4. In capillary, blood flow is very very slow.

width of total capillary is most big width in all of human blood vessel type. You can find explanation about this in high or middle school biology text book.

5. Some flower blooming related to time that exposed to sunlight.

Photoperiodism(W.W.Garner and H.A.Allard) is exactly that.

6. I guess that cancer growth related to time that exposed to enough sugar.

I guess sugar concentration and expose time is most important for cancer survival.

It is problem of input, store and cost. In low concentration, to store(or absorb) sugar costs much more energy than high concentration for same quantity. Osmotic pressure can explain the reason. In high concentration, cancer can store sugar(or ATP and etc) for low concentration. Cancer can survive without sugar input while the store(or energy) is not exhausted. Input of sugar related to store amount and cost amount. If input of sugar concentration is low or the time of Inputting is short, cancer may die of starving.

7. I have no idea about fat but I think to ingest no fat is good for cancer.

Membrane made of lipid. And phospholipid is important to membrane. And chemically, it's very hard to make lipid from carbohydrate. Carbohydrate have many hydroxyl groups. Hydroxyl group(R-COH-R) is more stable than carbon-hydrogen bond(R-CH2-R, R-CH=R). Carbohydrate is more stable than lipid.

8. I heard that cancer does not stop growing and segmenting.

It's not true? So, If It's not true, why cis-platinums attack segmenting cells( cis-platinums attack DNA. What is the evidence? that cis-platinums is cell cycle nonspecific. segmenting cells have only one important difference that only segmenting cells have mitosis phase and only mitosis phase exposes the DNA directly to danger of chemical attack for few minutes).

In korea education site, "cancer can not stay in G0 and that is reason that cancer segments without stopping." I'm not sure it's true. But I guess this site is believable. Unfortunately, it's korean site.

(http://kimwootae.com.ne.kr/generalbiology/cellcycle.htm)

Fortunately, I find it In english. At the last sentence of this site

(http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/CellCycle.html)

The disadvantage of cancer in poor environment

Cancer gain nutriment and oxygen from capillary(1th). In the blood vessel including capillary, blood flow is one way only. And in capillary, blood flow is very very slow(4th). And cancer does not stop growing and segmenting(8th). So cancer costs much sugar(2th, 3th, 8th). Gain nutriment and oxygen from capillary, one way flow, enough slow flow and cancer waste much sugar constantly. This four factor is all of the reason of the disadvantage. Tumor mass of cancer is a community of selfish cells. Cancer just absorb sugar so selfishly. As the foremost cancer cell absorb sugar so selfishly, the concentration getting lower(6th). In low concentration, absorbing sugar is more hard. And follow cancer cell can absorb more stingy sugar. At last, more than more than more stingy sugar is allowed for last cancer cell. Cancer cell can't control its waste in malnutrition. So proper malnutrition may can kill only cancer. Some specialist have a speculation that the biggest tumor mass of cancer inhibits other cancer mass from growing(reference, S. Biswas et al., "Inhibition of TGF-ß with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression" J. Clin. Invest. 117:1305-1313 (2007) ). This speculation can be explained by malnutrition. The biggest tumor mass of cancer cause little malnutrition and the malnutrition inhibits all of cancer mass from growing(on same meals). Other speculation can be explained by malnutrition

"Healthy Diet, Exercise Might Lower Chances of Cancer's Return

(http://www.healthyontario.com/NewsItemDetails.aspx?newsitem_id=220)"

In above news, tell us some fact that can be explained also by malnutrition.

'Vegetarian diet cause lower chances of cancer's return for only few years.'(In news)

Vegetarian diet has low calories and it cause slight malnutrition but as the time flows, human body can be adapted for vegetarian diet. So, after adaptation for vegetarian diet, there is no malnutrition. Therefore, there is no reason for lower chances of cancer's return after adaptation.

I think that the growth of cancer may depends on the blood-sugar level and the length of the time of enough blood-sugar level(Additionaly, the position of cancer and the size of tumor mass of cancer) like Photoperiodism(5th, 6th).

Generally, rich in vegetables and other plant-based foods mean lack of calorie. For example, calorie of cabbage 1kg is only 294 kcal(in Korea food & drug administration). But vegetables and other plant-based foods have various essential minerals and vitamins. In this writing, malnutrition means only lack of calorie. Absence of essential minerals and vitamins cause serious disease.

I am a korean and it's too hard to write with english to me(or for me? this is just a grammar confusion). So if you have great korean skill, I'll introduce my blog link(http://blog.naver.com/extra_rozer). I have no advertisement in my blog. I'm just have no Job. I'm studying for Job.

Since 11:41 am, 20, November, 1986 year, I always strive against fate with evils. Bless for bless. Evil to evil. So I'm evilstriver. Because my own fate is always evil since my birth.

P.S;

Anaerobic exercise is more good for fatness than aerobic but not good for wrinkles.{In fact, periodical exercise is related to increase of SOD. SOD can delay to aging by preventing active oxygens from get changed into free radical. So periodical anaerobic exercise is not much bad for aging}(about 1th)

If you ingest food with a little lipid, you may can get fat. but If you ingest food with no lipid, it's very hard to get fat. Unfortunately, it's too hard to ingest food without lipid.(In 7th)